What is Ceruloplasmin ?
Ceruloplasmin (CER) is the main transport protein for copper in the blood and plays a role in the body’s iron metabolism. Measuring levels of ceruloplasmin aids in the diagnosis of copper metabolism disorders. Various factors such as diet, hormone concentrations, and other genetic disorders, may influence plasma concentrations. Physical exercise, pregnancy (late), bile duct obstruction, primary biliary cirrhosis, patients on estrogen therapy, and leukemia exhibit increased levels of ceruloplasmin. Decreased levels are seen in Wilson’s disease, Menkes’s disease, Acute viral hepatitis, Nephrotic syndrome, gastroenteropathies, severe liver disease, malnutrition, and hypochromic anemia.
Hematologist, General physician, General Medicine